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KMID : 1038920220210030109
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Annals of Optometry and Contact Lens
2022 Volume.21 No. 3 p.109 ~ p.113
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The Matrix Metalloproteinase-9 Point-of-Care Test for Dry Eye Disease
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Kim Dong-Hyun
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Abstract
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Dry eye disease (DED) is a condition of the ocular surface characterized by tear film abnormalities and ocular symptoms; ocular surface inflammation is the principal pathogenesis. Recently, a matrix metalloproteinase-9 (MMP-9) point-of-care immunoassay (InflammaDry) has become widely used as an ancillary diagnostic tool in routine clinical settings. This paper reviews the role of MMP-9 in DED, the relationships of MMP-9-positivity on the InflammaDry test with the symptoms and signs of DED, and specific considerations when performing the test.
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KEYWORD
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Dry eye disease, MMP-9
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